ANTIBODIES

The present invention relates to antibodies binding to TREM1 and inhibiting its interaction with one or more of its natural ligands. Specific examples of such antibodies are provided. The therapeutic uses of the antibodies and methods of generating such are also provided. La présente invention conce...

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Main Authors LIGHTWOOD, Daniel John, SPILIOTOPOULOS, Anastasios, KEANEY, James Martin, ABENDROTH, Jan, DELKER, Silvia L, KADIU, Irena, BHATTA, Pallavi, ELLIOTT, Peter Charles
Format Patent
LanguageEnglish
French
Published 10.11.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to antibodies binding to TREM1 and inhibiting its interaction with one or more of its natural ligands. Specific examples of such antibodies are provided. The therapeutic uses of the antibodies and methods of generating such are also provided. La présente invention concerne des anticorps se liant à TREM1 et inhibant son interaction avec un ou plusieurs de ses ligands naturels. Des exemples spécifiques de tels anticorps sont décrits. L'invention concerne également les utilisations thérapeutiques des anticorps et des procédés de génération de ceux-ci.
Bibliography:Application Number: WO2022EP61661