FERRITIN VARIANTS WITH INCREASED STABILITY AND COMPLEXATION ABILITY

• Main Authors: BONAMORE, Alessandra, MARSZALEK, Ilona, SKORZYNSKI, Marcin, KROL, Magdalena, BOFFI, Alberto, RYGIEL, Tomasz, ARCOVITO, Alessandro
• Format: Patent
• Language: English; French
• Published: 22.09.2022
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention relates to a ferritin variant polypeptide, wherein at least one lysine residue is deleted or substituted with a non-basic amino acid. The invention further relates to a complex of this polypeptide and a label or drug, and an isolated cellular delivery system comprising the poly...