FXIA INHIBITOR COMPOUND IMPURITIES, AND PREPARATION METHOD AND USE THEREFOR

FXIa inhibitor compound impurities, and a preparation method and use therefor, comprising FXIa inhibitor compound impurity 1, impurity 2, and impurity 4. Also disclosed are a preparation method and use for the impurities. The provided FXIa inhibitor compound related impurities and the preparation me...

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Main Authors CHEN, Shujun, HUA, Huaijie, LI, Qinze, XU, Wenjie, CHEN, Xiangmeng, LIAN, Xiaolei
Format Patent
LanguageChinese
English
French
Published 22.09.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:FXIa inhibitor compound impurities, and a preparation method and use therefor, comprising FXIa inhibitor compound impurity 1, impurity 2, and impurity 4. Also disclosed are a preparation method and use for the impurities. The provided FXIa inhibitor compound related impurities and the preparation method therefor offer a basis for research of the quality of an FXIa inhibitor compound active pharmaceutical ingredient and a pharmaceutical composition thereof. L'invention concerne des impuretés de composé inhibiteur de FXIa, leur procédé de préparation et leur utilisation, comprenant l'impureté 1, l'impureté 2 et l'impureté 4 de composé inhibiteur de FXIa. L'invention concerne également un procédé de préparation et une utilisation pour les impuretés. Les impuretés associées à un composé inhibiteur de FXIa fournies et leur procédé de préparation offrent une base pour la recherche de la qualité d'un ingrédient pharmaceutique actif d'un composé inhibiteur de FXIa et une composition pharmaceutique de celui-ci. FXIa抑制
Bibliography:Application Number: WO2022CN81291