VACCINE COMPOSITION FOR PREVENTING SARS-COV-2

• Main Authors: KIM, Kwangsung, CHO, Yang Je, KIM, Seok Hyun
• Format: Patent
• Language: English; French; Korean
• Published: 15.09.2022
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to a vaccine composition for preventing SARS-CoV-2, comprising mRNA encoding an S mutant antigen of SARS-CoV-2 virus, wherein a vaccine for preventing SARS-CoV-2 according to the present invention exhibits excellent stability and high immunogenicity in vivo, and the vaccine is thus easy to store and use, and excellent preventive effect thereof against COVID-19 can be expected. La présente invention concerne une composition vaccinale pour prévenir le SARS-CoV-2, comprenant l'ARNm codant pour un antigène mutant S du virus du SARS-CoV-2, un vaccin pour prévenir le SARS-CoV-2 selon la présente invention présentant une excellente stabilité et une immunogénicité élevée in vivo, et le vaccin étant ainsi facile à stocker et à utiliser, et un excellent effet préventif de celui-ci contre la COVID-19 pouvant être attendu. 본 발명은 SARS-CoV-2 바이러스의 S 변이 항원을 코딩하는 mRNA를 포함하는 SARS-CoV-2 예방용 백신 조성물에 관한 것으로, 본 발명에 따른 SARS-CoV-2 예방 백신은 우수한 안정성과 in vivo에서 높은 면역원성을 나타내어, 백신의 보관 및 사용이 간편하고, 코로나 19에 대한 뛰어난 예방효과를 기대할 수 있다.