PREPARATION OF SIGLEC-15 BINDING PROTEIN AND USE THEREOF

• Main Authors: DENG, Sujun, PAN, Zhongzong, WANG, Zongda, YANG, Xinxiu, WANG, Xueping, YANG, Lu, LIU, Peipei, LIU, Xiaowu, GU, Chunyin, CAO, Xiaodan
• Format: Patent
• Language: Chinese; English; French
• Published: 01.09.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The present invention provides a preparation of a Siglec-15 binding protein and the use thereof, and specifically relates to an isolated antigen-binding protein, which comprises HCDR3. Provided is the use of the antigen-binding protein in the prevention and treatment of diseases. La présente invention concerne une préparation d'une protéine de liaison de Siglec-15 et son utilisation, et concerne en particulier une protéine de liaison à l'antigène isolée, qui comprend HCDR3. L'invention concerne l'utilisation de la protéine de liaison à l'antigène dans la prévention et le traitement de maladies. 一种Siglec-15结合蛋白的制备及其用途，具体涉及一种分离的抗原结合蛋白，包含HCDR3。提供了所述抗原结合蛋白在预防和治疗疾病中的应用。