ANTI-PD-1 ANTIBODY AND USE THEREOF

Provided is an isolated antigen-binding protein capable of binding to a PD-1 protein, capable of blocking binding between a PD-1 protein and a PD-L1 and/or PD-L2 protein, and/or capable of stimulating immune cells to secrete cytokines. Also provided is a use of the isolated antigen-binding protein i...

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Bibliographic Details
Main Authors DENG, Sujun, PAN, Zhongzong, WANG, Zongda, YANG, Xinxiu, WANG, Xueping, LIU, Xiaowu, GU, Chunyin, CAO, Xiaodan
Format Patent
LanguageChinese
English
French
Published 18.08.2022
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Summary:Provided is an isolated antigen-binding protein capable of binding to a PD-1 protein, capable of blocking binding between a PD-1 protein and a PD-L1 and/or PD-L2 protein, and/or capable of stimulating immune cells to secrete cytokines. Also provided is a use of the isolated antigen-binding protein in preparation of medicaments. L'invention concerne une protéine de liaison à l'antigène isolée capable de se lier à une protéine PD-1, capable de bloquer la liaison entre une protéine PD-1 et une protéine PD-L1 et/ou PD-L2, et/ou capable de stimuler des cellules immunitaires pour sécréter des cytokines. L'invention concerne également une utilisation de la protéine de liaison à l'antigène isolée dans la préparation de médicaments. 提供了一种分离的抗原结合蛋白,其能够结合PD-1蛋白,能够阻断PD-1蛋白与PD-L1和/或PD-L2蛋白之间的结合,和/或,能够刺激免疫细胞分泌细胞因子。还提供了所述分离的抗原结合蛋白在制备药物中的用途。
Bibliography:Application Number: WO2022CN75593