ANTIBODY COMBINATION THERAPIES FOR SARS-COV-2 INFECTION
The present disclosure provides antibody combinations and related methods for treating a SARS-CoV-2 infection in a subject or for manufacturing a medicament for the treatment of a SARS-CoV-2 infection. In some aspects, a therapy, composition, or combination can include two or three antibodies that b...
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| Main Authors | , , , , , , , , |
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| Format | Patent |
| Language | English French |
| Published |
28.07.2022
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present disclosure provides antibody combinations and related methods for treating a SARS-CoV-2 infection in a subject or for manufacturing a medicament for the treatment of a SARS-CoV-2 infection. In some aspects, a therapy, composition, or combination can include two or three antibodies that bind to different epitopes on a SARS-CoV-2 surface (S) glycoprotein. The antibody combinations can potently neutralize SARS-CoV-2. Antibody compositions comprising such combinations are also provided.
La présente divulgation concerne des combinaisons d'anticorps et des méthodes associées pour traiter une infection par SARS-CoV-2 chez un sujet ou pour fabriquer un médicament pour le traitement d'une infection par SARS-CoV-2. Dans certains aspects, une thérapie, une composition ou une combinaison peuvent comprendre deux ou trois anticorps qui se lient à différents épitopes sur une glycoprotéine de surface (S) de SARS-CoV-2. Les combinaisons d'anticorps peuvent neutraliser puissamment le SARS-CoV-2. L'invention concerne également des compositions d'anticorps comprenant de telles combinaisons. |
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| AbstractList | The present disclosure provides antibody combinations and related methods for treating a SARS-CoV-2 infection in a subject or for manufacturing a medicament for the treatment of a SARS-CoV-2 infection. In some aspects, a therapy, composition, or combination can include two or three antibodies that bind to different epitopes on a SARS-CoV-2 surface (S) glycoprotein. The antibody combinations can potently neutralize SARS-CoV-2. Antibody compositions comprising such combinations are also provided.
La présente divulgation concerne des combinaisons d'anticorps et des méthodes associées pour traiter une infection par SARS-CoV-2 chez un sujet ou pour fabriquer un médicament pour le traitement d'une infection par SARS-CoV-2. Dans certains aspects, une thérapie, une composition ou une combinaison peuvent comprendre deux ou trois anticorps qui se lient à différents épitopes sur une glycoprotéine de surface (S) de SARS-CoV-2. Les combinaisons d'anticorps peuvent neutraliser puissamment le SARS-CoV-2. L'invention concerne également des compositions d'anticorps comprenant de telles combinaisons. |
| Author | YEH, Wendy JONES, Bryan Edward PANG, Phillip S VIRGIN, Herbert W LEMPP, Florian CORTI, Davide HEBNER, Christy M MOGALIAN, Erik ADAMS, Andrew Charles |
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| DocumentTitleAlternate | POLYTHÉRAPIES À BASE D'ANTICORPS CONTRE UNE INFECTION PAR SARS-COV-2 |
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| RelatedCompanies | ELI LILLY AND COMPANY VIR BIOTECHNOLOGY, INC |
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| Snippet | The present disclosure provides antibody combinations and related methods for treating a SARS-CoV-2 infection in a subject or for manufacturing a medicament... |
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| Title | ANTIBODY COMBINATION THERAPIES FOR SARS-COV-2 INFECTION |
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