POLY(GLYCEROL SEBACATE) URETHANE ELASTOMERIC LEAFLET FOR HEART VALVE REPLACEMENT

• Main Authors: GABRIELE, Peter D, STAHL, Alexander M, REED, Stephanie, WEBER, Amanda K, METZGER, Andrew
• Format: Patent
• Language: English; French
• Published: 14.07.2022
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL

A leaflet for a heart valve replacement includes poly(glycerol sebacate) urethane. A heart valve replacement includes a leaflet including poly(glycerol sebacate) urethane. A process forms a leaflet for a heart valve replacement. The process includes casting a first solution including poly(glycerol sebacate) and isocyanate to form a leaflet composition including poly(glycerol sebacate) urethane. The process also includes shaping the leaflet composition to form the leaflet. Un feuillet pour remplacement de valvule cardiaque comprend de l'uréthane de poly(glycérol sébacate). Un remplacement de valvule cardiaque comprend un feuillet comprenant de l'uréthane de poly(glycérol sébacate). Un procédé forme un feuillet pour un remplacement de valvule cardiaque. Le procédé comprend le coulage d'une première solution comprenant du poly(glycérol sébacate) et de l'isocyanate pour former une composition de feuillet comprenant de l'uréthane de poly(glycérol sébacate). Le procédé comprend également la mise en forme de la composition de feuillet pour former le feuillet.