TOPICAL COMPOSITIONS AND METHODS OF TREATING SKIN DISEASES AND CONDITIONS WITH SUCH COMPOSITIONS

A pharmaceutical composition is provided including tamibarotene or a salt or analog thereof, a solubilizer, a permeation enhancer, a polymeric emulsifier, and a surfactant. In a further preferred embodiment, the pharmaceutical composition is in the form of a gel or cream, and provides a smooth compo...

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Bibliographic Details
Main Authors VALIA, Kirti H, KAPLAN, David, DURRANI, Samedyar, DURRANI, Manzer J
Format Patent
LanguageEnglish
French
Published 30.06.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A pharmaceutical composition is provided including tamibarotene or a salt or analog thereof, a solubilizer, a permeation enhancer, a polymeric emulsifier, and a surfactant. In a further preferred embodiment, the pharmaceutical composition is in the form of a gel or cream, and provides a smooth composition to apply to the skin. The invention is further directed to methods of manufacturing the pharmaceutical composition and methods of treating a patient's skin with the pharmaceutical composition. L'invention concerne une composition pharmaceutique comprenant du tamibarotène ou un sel ou analogue de celui-ci, un solubilisant, un facilitateur de perméation, un émulsifiant polymère et un tensioactif. Dans un autre mode de réalisation préféré, la composition pharmaceutique se présente sous la forme d'un gel ou d'une crème, et fournit une composition lisse à appliquer sur la peau. L'invention concerne en outre des procédés de fabrication de la composition pharmaceutique et des procédés de traitement de la peau d'un patient avec la composition pharmaceutique.
Bibliography:Application Number: WO2021US64729