ISOXAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO

Provided is a compound of Formula (I) or a pharmaceutically acceptable salt thereof, that is a modulator of 5-HT2A and can be used in treating diseases and disorders associated with 5-HT2A serotonin receptor expression and/or activity. Thus, also provided are methods of treating 5HT2A-related diseas...

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Bibliographic Details
Main Authors SEMPLE, Graeme, TRAN, Thuy-Anh
Format Patent
LanguageEnglish
French
Published 05.05.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Provided is a compound of Formula (I) or a pharmaceutically acceptable salt thereof, that is a modulator of 5-HT2A and can be used in treating diseases and disorders associated with 5-HT2A serotonin receptor expression and/or activity. Thus, also provided are methods of treating 5HT2A-related diseases and disorders. L'invention concerne un composé de formule (I) ou un sel pharmaceutiquement acceptable de celui-ci, qui est un modulateur du 5-HT2A et peut être utilisé dans le traitement de maladies et de troubles associés à l'expression et/ou à l'activité du récepteur sérotoninergique 5-HT2A. Ainsi, l'invention concerne également des procédés de traitement de maladies et de troubles liés au 5-HT2A.
Bibliography:Application Number: WO2021US56694