ANTIBODY SCAFFOLD STRUCTURE

Provided herein are antibodies comprising a scaffold region and methods of using such antibodies to generate antibodies with binding specificities that differ from a parent antibody that comprises the scaffold region. L'invention concerne des anticorps comprenant une région d'échafaudage e...

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Bibliographic Details
Main Authors FINN, Jessica, LIPPOW, Shaun M
Format Patent
LanguageEnglish
French
Published 21.04.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are antibodies comprising a scaffold region and methods of using such antibodies to generate antibodies with binding specificities that differ from a parent antibody that comprises the scaffold region. L'invention concerne des anticorps comprenant une région d'échafaudage et des méthodes d'utilisation de tels anticorps pour générer des anticorps ayant des spécificités de liaison qui diffèrent d'un anticorps parent comprenant la région d'échafaudage.
Bibliography:Application Number: WO2021US54983