AAV8 AFFINITY AGENTS

Provided herein are affinity ligands that specifically interact with AAV8 capsid and/or AAV8 variant capsid, affinity agents comprising the affinity ligands, and methods of their use for binding, isolation, and/or purification of AAV8 and variants thereof. L'invention concerne des ligands d...

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Main Authors BHATTACHARYA, Sarmistha, VALENTINI, Sarah, COYLE, Brandon, KEARNS, Kelley, SCANLON, Thomas, KETT, Warren, WELLBORN, William
Format Patent
LanguageEnglish
French
Published 21.04.2022
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
TRANSPORTING
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Summary:Provided herein are affinity ligands that specifically interact with AAV8 capsid and/or AAV8 variant capsid, affinity agents comprising the affinity ligands, and methods of their use for binding, isolation, and/or purification of AAV8 and variants thereof. L'invention concerne des ligands d'affinité qui interagissent spécifiquement avec une capside AAV8 et/ou un variant AAV8, des agents d'affinité comprenant les ligands d'affinité, et des procédés d'utilisation de ceux-ci pour la liaison, l'isolement et/ou la purification d'AAV8 et de variants de ceux-ci.
Bibliography:Application Number: WO2021US54870