DEVELOPMENT AND APPLICATION OF POLYMER-COATED GOLD NANOPARTICLE-APTAMER NANOCONSTRUCT HAVING SENSITIVITY TO REACTIVE OXYGEN SPECIES
The present invention relates to a polymer-coated gold nanoparticle-aptamer nanoconstruct that has sensitivity to reactive oxygen species and can treat inflammatory diseases by the capture of reactive oxygen species and TNF-α. La présente invention concerne une nanoconstruction du type aptamère-nano...
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Main Authors | , , |
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Format | Patent |
Language | English French Korean |
Published |
14.04.2022
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to a polymer-coated gold nanoparticle-aptamer nanoconstruct that has sensitivity to reactive oxygen species and can treat inflammatory diseases by the capture of reactive oxygen species and TNF-α.
La présente invention concerne une nanoconstruction du type aptamère-nanoparticule d'or revêtue de polymère qui présente une sensibilité vis-à-vis de dérivés réactifs de l'oxygène (ROS) et qui peut traiter des maladies inflammatoires par capture de dérivés réactifs de l'oxygène et de TNF-α.
본 발명은 활성산소종 감응성을 가지고, 활성산소종 포집 및 TNF-α 포집을 통해 염증성 질환을 치료할 수 있는, 고분자가 코팅된 금 나노입자-압타머 나노구조체에 관한 것이다. |
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Bibliography: | Application Number: WO2021KR13605 |