METHOD FOR PREDICTING THE EFFICIENCY OF A TREATMENT STIMULATING AN IFN-BETA DEPENDENT ADAPTIVE IMMUNE RESPONSE VIA DETECTION OF A SINGLE NUCLEOTIDE POLYMORPHISM

• Main Authors: ASSOUVIE, Anaïs, ROUSSELET, Germain
• Format: Patent
• Language: English; French
• Published: 14.04.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

The present invention relates to a method for predicting the efficiency of a treatment stimulating an IFN-β dependent adaptive immune response, comprising a step of detecting the rs12553564 single nucleotide polymorphism (SNP), or an SNP in high linkage disequilibrium with same, said SNP being selected from rs12551341, rs2275888, and rs10811449, in a biological sample of a subject in need thereof. La présente invention concerne un procédé de prédiction de l'efficacité d'un traitement stimulant une réponse immunitaire adaptative dépendant de l'IFN-bêta, comprenant une étape de détection du polymorphisme mononucléotidique rs12553564 (SNP), ou d'un SNP en déséquilibre de liaison élevé avec celui-ci, ledit SNP étant choisi parmi rs12551341, rs2275888, et rs10811449, dans un échantillon biologique d'un sujet en ayant besoin.