METHODS AND COMPOSITIONS FOR TREATING GLIOBLASTOMA

The current disclosure provides for novel multi-specific CAR molecules for the treatment of glioblastoma (also called GBM or glioblastoma multiforme). This disclosure also describes nucleic acids encoding for the polypeptides, expression vectors comprising the nucleic acids, cells and/or populations...

Full description

Saved in:
Bibliographic Details
Main Authors HOU, Andrew J, CHEN, Yvonne Yu-Hsuan
Format Patent
LanguageEnglish
French
Published 07.04.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The current disclosure provides for novel multi-specific CAR molecules for the treatment of glioblastoma (also called GBM or glioblastoma multiforme). This disclosure also describes nucleic acids encoding for the polypeptides, expression vectors comprising the nucleic acids, cells and/or populations of cells expressing the polypeptides and/or comprising the nucleic acids or expression vectors of the disclosure, and compositions comprising the polypeptides, nucleic acids, or cells. La présente invention concerne de nouvelles molécules CAR multi-spécifiques pour le traitement du glioblastome (également appelé GBM ou glioblastome multiforme). L'invention concerne également des acides nucléiques codant pour les polypeptides, des vecteurs d'expression comprenant les acides nucléiques, des cellules et/ou des populations de cellules exprimant les polypeptides et/ou comprenant les acides nucléiques ou les vecteurs d'expression de l'invention, et des compositions comprenant les polypeptides, les acides nucléiques ou les cellules.
Bibliography:Application Number: WO2021US47600