COMPOSITION FOR PREVENTING HAIR LOSS OR PROMOTING HAIR GROWTH CONTAINING LAGERSTROEMIA INDICA EXTRACT AS ACTIVE INGREDIENT

• Main Authors: KIM, Myong Ki, CHOI, Hyuk-Jun, JANG, Wook Ju, OH, Kyung-Eon, CHOI, Bu Young
• Format: Patent
• Language: English; French; Korean
• Published: 03.03.2022
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention relates to a composition for preventing hair loss or promoting hair growth and, specifically, to a cosmetic composition, a pharmaceutical composition and a health food composition for preventing hair loss or promoting hair growth, containing a Lagerstroemia indica extract as an active ingredient. The Lagerstroemia indica extract can effectively induce or promote the growth of dermal papilla cells by activating WNT signaling and inhibiting TGF-β signaling, thus more effectively preventing hair loss or promoting hair growth. In addition, the extract is a natural substance, and thus has the advantages of fewer side effects and being safe. La présente invention concerne une composition pour prévenir la chute des cheveux ou favoriser la pousse des cheveux et, de manière spécifique, une composition cosmétique, une composition pharmaceutique et une composition alimentaire diététique pour prévenir la chute des cheveux ou favoriser la pousse des cheveux, contenant un extrait de Lagerstroemia indica en tant que principe actif. L'extrait de Lagerstroemia indica peut induire ou favoriser efficacement la croissance de cellules de papille dermique par activation de la signalisation de WNT et inhibition de la signalisation de TGF-β, empêchant ainsi de manière plus efficace la chute des cheveux ou favorisant ainsi de manière plus efficace la pousse des cheveux. De plus, l'extrait est une substance naturelle, et présente ainsi les avantages d'avoir moins d'effets secondaires et d'être sûr. 본 발명은 탈모 방지 또는 발모 촉진용 조성물에 관한 것으로, 상세하게는 배롱나무(Lagerstroemia indica) 추출물을 유효성분으로 함유하는 탈모 방지 또는 발모 촉진용 화장료 조성물, 약학 조성물, 및 건강식품 조성물을 제공한다. 상기 배롱나무 추출물은 WNT 신호 전달을 활성화하고 TGF-β의 신호 전달을 억제함으로써 모유두 세포의 성장을 효과적으로 유도하거나 촉진시켜 보다 효과적으로 탈모를 방지하거나 발모를 촉진시킬 수 있다. 또한, 천연물로써 부작용이 적고 안전한 장점을 가진다.