ENRICHMENT OF T CELLS USING AN ANTI-Cß ANTIBODY

• Main Authors: SOMMERMEYER, Daniel, MILOSEVIC, Slavoljub, SCHLEICHER, Anna
• Format: Patent
• Language: English; French
• Published: 24.02.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present invention describes methods and uses of antibodies targeting the Cβ1 or the Cβ2 chain of a TCR, in particular an anti-Cβ1 antibody, for enrichment of T cells expressing a desired antigen-specific recombinant T cell receptor (TCR). La présente invention concerne des méthodes et des utilis...