ENRICHMENT OF T CELLS USING AN ANTI-Cß ANTIBODY

The present invention describes methods and uses of antibodies targeting the Cβ1 or the Cβ2 chain of a TCR, in particular an anti-Cβ1 antibody, for enrichment of T cells expressing a desired antigen-specific recombinant T cell receptor (TCR). La présente invention concerne des méthodes et des utilis...

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Bibliographic Details
Main Authors SOMMERMEYER, Daniel, MILOSEVIC, Slavoljub, SCHLEICHER, Anna
Format Patent
LanguageEnglish
French
Published 24.02.2022
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention describes methods and uses of antibodies targeting the Cβ1 or the Cβ2 chain of a TCR, in particular an anti-Cβ1 antibody, for enrichment of T cells expressing a desired antigen-specific recombinant T cell receptor (TCR). La présente invention concerne des méthodes et des utilisations d'anticorps ciblant la chaîne Cβ1 ou Cβ2 d'un TCR, en particulier un anticorps anti-Cβ1, pour l'enrichissement de lymphocytes T exprimant un récepteur recombinant de lymphocytes T (TCR) spécifique d'un antigène souhaité.
Bibliography:Application Number: WO2021EP72792