METHODS TO USE FLAVONOIDS FOR INHIBITION OF SARS-COV-2 AND TREATMENT OF COVID-19

Compositions and methods for treating viral infections, such as Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infections, are described. The compositions can include flavan-3-ols, proanthocyanidins, flavones, flavonols, and/or dihydroflavonols. Also described are methods and compositi...

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Main Authors XIE, Deyu, ZHU, Yue
Format Patent
LanguageEnglish
French
Published 17.02.2022
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Abstract Compositions and methods for treating viral infections, such as Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infections, are described. The compositions can include flavan-3-ols, proanthocyanidins, flavones, flavonols, and/or dihydroflavonols. Also described are methods and compositions for inhibiting the main protease of SARS-CoV-2 and methods and compositions for inhibiting binding of human angiotensin-converting enzyme 2 (hACE2) and SARS-CoV-2 spike (S) protein. L'invention concerne des compositions et des méthodes de traitement d'infections virales, telles que des infections du coronavirus 2 du syndrome respiratoire aigu sévère (SARS-CoV-2). Les compositions peuvent comprendre des flavan-3-ols, des proanthocyanidines, des flavones, des flavonols et/ou des dihydroflavonols. L'invention concerne également des méthodes ainsi que des compositions pour inhiber la protéase principale du SARS-CoV-2 et des méthodes ainsi que des compositions pour inhiber la liaison de l'enzyme 2 de conversion de l'angiotensine humaine (hACE2) et de la protéine de spicule (S) du SARS-CoV-2.
AbstractList Compositions and methods for treating viral infections, such as Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infections, are described. The compositions can include flavan-3-ols, proanthocyanidins, flavones, flavonols, and/or dihydroflavonols. Also described are methods and compositions for inhibiting the main protease of SARS-CoV-2 and methods and compositions for inhibiting binding of human angiotensin-converting enzyme 2 (hACE2) and SARS-CoV-2 spike (S) protein. L'invention concerne des compositions et des méthodes de traitement d'infections virales, telles que des infections du coronavirus 2 du syndrome respiratoire aigu sévère (SARS-CoV-2). Les compositions peuvent comprendre des flavan-3-ols, des proanthocyanidines, des flavones, des flavonols et/ou des dihydroflavonols. L'invention concerne également des méthodes ainsi que des compositions pour inhiber la protéase principale du SARS-CoV-2 et des méthodes ainsi que des compositions pour inhiber la liaison de l'enzyme 2 de conversion de l'angiotensine humaine (hACE2) et de la protéine de spicule (S) du SARS-CoV-2.
Author XIE, Deyu
ZHU, Yue
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DocumentTitleAlternate MÉTHODES D'UTILISATION DE FLAVONOÏDES POUR L'INHIBITION DU SARS-COV-2 ET LE TRAITEMENT DE LA COVID-19
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Snippet Compositions and methods for treating viral infections, such as Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infections, are described. The...
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PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title METHODS TO USE FLAVONOIDS FOR INHIBITION OF SARS-COV-2 AND TREATMENT OF COVID-19
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