METHODS TO USE FLAVONOIDS FOR INHIBITION OF SARS-COV-2 AND TREATMENT OF COVID-19

Compositions and methods for treating viral infections, such as Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infections, are described. The compositions can include flavan-3-ols, proanthocyanidins, flavones, flavonols, and/or dihydroflavonols. Also described are methods and compositi...

Full description

Saved in:
Bibliographic Details
Main Authors XIE, Deyu, ZHU, Yue
Format Patent
LanguageEnglish
French
Published 17.02.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:Compositions and methods for treating viral infections, such as Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infections, are described. The compositions can include flavan-3-ols, proanthocyanidins, flavones, flavonols, and/or dihydroflavonols. Also described are methods and compositions for inhibiting the main protease of SARS-CoV-2 and methods and compositions for inhibiting binding of human angiotensin-converting enzyme 2 (hACE2) and SARS-CoV-2 spike (S) protein. L'invention concerne des compositions et des méthodes de traitement d'infections virales, telles que des infections du coronavirus 2 du syndrome respiratoire aigu sévère (SARS-CoV-2). Les compositions peuvent comprendre des flavan-3-ols, des proanthocyanidines, des flavones, des flavonols et/ou des dihydroflavonols. L'invention concerne également des méthodes ainsi que des compositions pour inhiber la protéase principale du SARS-CoV-2 et des méthodes ainsi que des compositions pour inhiber la liaison de l'enzyme 2 de conversion de l'angiotensine humaine (hACE2) et de la protéine de spicule (S) du SARS-CoV-2.
Bibliography:Application Number: WO2021US46129