ANTIVIRAL COMPOSITION AGAINST CORONAVIRUS

• Main Authors: KIM, Won Keun, KIM, Tai Hyun, OH, Kwang Ji
• Format: Patent
• Language: English; French; Korean
• Published: 10.02.2022
• Subjects: CHEMISTRY; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention relates to an antiviral composition against coronavirus. More specifically, the antiviral composition comprises an antibody or fragment thereof, comprising heavy chain CDR1 (VH CDR1) represented by SEQ ID NO: 1, VH CDR2 represented by SEQ ID NO: 2, VH CDR3 represented by SEQ ID NO: 3, light chain CDR1(VL CDR1) represented by SEQ ID NO: 4, VL CDR2 represented by SEQ ID NO: 5, and VL CDR3 represented by SEQ ID NO: 6, thereby exhibiting an excellent antiviral effect against coronavirus, and an effect of preventing, treating, or ameliorating diseases caused by coronavirus. La présente invention concerne une composition antivirale contre le coronavirus. Plus particulièrement, la composition antivirale comprend un anticorps ou un fragment de celui-ci, comprenant une chaîne lourde CDR1 (VH CDR1) représentée par SEQ ID NO : 1, VH CDR2 représentée par SEQ ID NO : 2, VH CDR3 représentée par SEQ ID NO : 3, une chaîne légère CDR1 (VL CDR1) représentée par SEQ ID NO : 4, VL CDR2 représentée par SEQ ID NO : 5, et VL CDR3 représentée par SEQ ID NO : 6, présentant ainsi un excellent effet antiviral contre le coronavirus, et un effet de prévention, de traitement ou d'amélioration de maladies provoquées par un coronavirus. 본 발명은 코로나바이러스에 대한 항바이러스용 조성물에 관한 것으로, 보다 상세하게는 서열번호 1로 표시되는 중쇄 CDR1(VH CDR1), 서열번호 2로 표시되는 VH CDR2, 및 서열번호 3으로 표시되는 VH CDR3, 서열번호 4로 표시되는 경쇄 CDR1(VL CDR1), 서열번호 5로 표시되는 VL CDR2 및 서열번호 6으로 표시되는 VL CDR3을 포함하는 항체 또는 이의 단편을 포함함으로써 코로나바이러스에 대한 우수한 항바이러스 효과를 나타내고, 코로나바이러스에 의해 유발되는 질환의 예방, 치료 또는 개선 효과를 나타낸다.