ANTI-BETACELLULIN ANTIBODIES, FRAGMENTS THEREOF, AND MULTI-SPECIFIC BINDING MOLECULES

The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BT...

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Main Authors QIU, Yubin, TOKSOZ, Engin, HANKS, Shawn Michael, GHOSH, Joy Gispati, MOKER, Nina, BIGELOW, Chad Eric, TWAROG, Michael Zbigniew, HAUBST, Nicole, CHASTAIN, James Edgar, STEFANIDAKIS, Michael, ETEMAD-GILBERTSON, Bijan Alexandre, CARRION, Ana Maria, POOR, Stephen Hendrick, NGUYEN, Andrew Anh, IYER, Ganesh Rajan, RANGASWAMY, Nalini Velamur, CLARK, Kirk Lee
Format Patent
LanguageEnglish
French
Published 20.01.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BTC binding moiety and an anti-VEGF binding moiety. La présente invention concerne des anticorps anti-BTC, des procédés de production desdits anticorps, des compositions pharmaceutiques comprenant lesdits anticorps, et des méthodes d'utilisation desdits anticorps. La présente invention concerne également des molécules de liaison multi-spécifiques, par exemple des anticorps bispécifiques, comprenant une fraction de liaison à BTC et une fraction de liaison anti-VEGF.
Bibliography:Application Number: WO2021IB56363