METHOTREXATE ANALOGS AND METHODS OF USE

Compounds having general formula (I) or a pharmaceutically acceptable salt, N-oxide, or hydrate thereof are provided herein. Also provided are methods of making the compounds and methods of their use, including in treatment of cancer, autoimmune disorders, and viral infections. L'invention conc...

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Bibliographic Details
Main Authors RAI BANTUKALLU, Ganesha, LAMY, Laurence, INGLESE, James, RANA, Sandeep
Format Patent
LanguageEnglish
French
Published 30.12.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds having general formula (I) or a pharmaceutically acceptable salt, N-oxide, or hydrate thereof are provided herein. Also provided are methods of making the compounds and methods of their use, including in treatment of cancer, autoimmune disorders, and viral infections. L'invention concerne des composés de formule générale (I) ou un sel, N-oxyde ou hydrate pharmaceutiquement acceptable de ceux-ci. L'invention concerne également des procédés de fabrication des composés et des procédés d'utilisation de ceux-ci, notamment dans le traitement du cancer, de troubles auto-immuns et d'infections virales.
Bibliography:Application Number: WO2021US38441