COMPOSITIONS AND METHODS FOR TREATING COVID-19

• Main Authors: WANG, Ying, LAI, Norman Zhennan, TAN, Yuebin
• Format: Patent
• Language: English; French
• Published: 23.12.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

This disclosure is directed to inhibitory oligonucleotides, inhibitory peptides, compositions and methods for preventing or treating Coronavirus disease 2019 (COVID-19). In one aspect, the disclosure is directed to compositions that comprise inhibitory oligonucleotides against one or more SARS-CoV-2 virus genes. In another aspect, the disclosure is directed to compositions that comprise inhibitory peptides that inhibit SARS-COV-2 entry into cells. Another aspect of the disclosure is directed to gene therapy methods for treating COVID-19, and vectors for carrying out the same. Finally, the disclosure provides nutritional supplements to support human immunity and prevent or inhibit viral infections. La présente divulgation concerne des oligonucléotides inhibiteurs, des peptides inhibiteurs, des compositions et des méthodes de prévention ou de traitement d'une maladie à coronavirus 2019 (COVID-19). Selon un aspect, la divulgation concerne des compositions comprenant des oligonucléotides inhibiteurs contre un ou plusieurs gènes du virus du SARS-CoV-2. Selon un autre aspect, la divulgation concerne des compositions comprenant des peptides inhibiteurs qui inhibent l'entrée du SARS-COV-2 dans des cellules. Un autre aspect encore de la divulgation concerne des méthodes de thérapie génique de traitement de la COVID-19, et des vecteurs permettant leur mise en œuvre. Enfin, l'invention concerne des compléments alimentaires destinés à favoriser l'immunité humaine et à prévenir ou à inhiber des infections virales.