METHODS FOR TREATING SEVERE ASTHMA IN PATIENTS WITH NASAL POLYPOSIS

Provided herein are methods of reducing exacerbations of asthma in an asthma patient with nasal polyposis, comprising administering to the patient an effective amount of the anti-interleukin-5 receptor (IL-5R) antibody benralizumab or an antigen-binding fragment thereof. L'invention concerne de...

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Bibliographic Details
Main Authors ZANGRILLI, James, BURDEN, Anne, KREINDLER, James, GARCIA GIL, Maria Esther
Format Patent
LanguageEnglish
French
Published 09.12.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are methods of reducing exacerbations of asthma in an asthma patient with nasal polyposis, comprising administering to the patient an effective amount of the anti-interleukin-5 receptor (IL-5R) antibody benralizumab or an antigen-binding fragment thereof. L'invention concerne des méthodes permettant de réduire les exacerbations d'asthme chez un patient asthmatique atteint d'une polypose nasale, comprenant l'administration au patient d'une quantité efficace de benralizumab, un anticorps qui se lie au récepteur de l'interleukine-5 (IL-5R) ou d'un fragment de liaison à l'antigène de celui-ci.
Bibliography:Application Number: WO2021IB54921