OPTIMIZED NUCLEOTIDE SEQUENCES ENCODING SARS-COV-2 ANTIGENS

• Main Authors: KALNIN, Kirill, DEROSA, Frank, FU, Tong-Ming, CHIVUKULA, Sudha, KARVE, Shrirang, TRAN, Khang, PLITNIK, Timothy, DUBINS, Jeffrey, GU, Xiaobo, ZACHARIA, Minnie, DIAS, Anusha, SKALESKI, Joseph, BOEGLIN, Lianne, CASIMIRO, Danilo
• Format: Patent
• Language: English; French
• Published: 10.11.2022
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to optimized nucleotide sequence encoding SARS-CoV-2 antigens. These sequences are particularly suitable for use in vaccine compositions for the treatment or prevention of infections caused by a β-coronaviruses, including COVID-19 infections, in a human or animal subjec...