OPTIMIZED NUCLEOTIDE SEQUENCES ENCODING SARS-COV-2 ANTIGENS

The present invention relates to optimized nucleotide sequence encoding SARS-CoV-2 antigens. These sequences are particularly suitable for use in vaccine compositions for the treatment or prevention of infections caused by a β-coronaviruses, including COVID-19 infections, in a human or animal subjec...

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Main Authors KALNIN, Kirill, DEROSA, Frank, FU, Tong-Ming, CHIVUKULA, Sudha, KARVE, Shrirang, TRAN, Khang, PLITNIK, Timothy, DUBINS, Jeffrey, GU, Xiaobo, ZACHARIA, Minnie, DIAS, Anusha, SKALESKI, Joseph, BOEGLIN, Lianne, CASIMIRO, Danilo
Format Patent
LanguageEnglish
French
Published 10.11.2022
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Summary:The present invention relates to optimized nucleotide sequence encoding SARS-CoV-2 antigens. These sequences are particularly suitable for use in vaccine compositions for the treatment or prevention of infections caused by a β-coronaviruses, including COVID-19 infections, in a human or animal subject in need of such treatment. La présente invention se rapporte à une séquence nucléotidique optimisée codant pour des antigènes du SARS-CoV-2. Ces séquences sont particulièrement appropriées pour être utilisées dans des compositions de vaccin pour le traitement ou la prévention d'infections provoquées par des β-coronavirus, y compris des infections par la COVID-19, chez un sujet humain ou un animal ayant besoin d'un tel traitement.
Bibliography:Application Number: WO2021US31256