COMPOSITION FOR CILIOGENESIS PROMOTION, CONTAINING, AS ACTIVE INGREDIENT, MESENCHYMAL STEM CELL OR MESENCHYMAL STEM CELL CULTURE SOLUTION

• Main Authors: CHANG, Jong Wook, JEON, Hong Bae, PARK, Sang Eon
• Format: Patent
• Language: English; French; Korean
• Published: 30.09.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; SPIRITS; VINEGAR; WINE

Provided in the present invention is a composition for ciliogenesis, containing a mesenchymal stem cell or a mesenchymal stem cell culture product. The mesenchymal stem cell or a mesenchymal stem cell culture product, according to the present invention, increases the number of primary cilia in cells and elongates same. The mesenchymal stem cell or the mesenchymal stem cell culture product, according to the present invention, can be used as a pharmaceutical composition for preventing or treating diseases caused by ciliopathy or ciliary impairment. The mesenchymal stem cell or the mesenchymal stem cell culture product, according to the present invention, can be used as a cosmetic composition. La présente invention concerne une composition pour la ciliogenèse, contenant une cellule souche mésenchymateuse ou un produit de culture de cellules souches mésenchymateuses. La cellule souche mésenchymateuse ou un produit de culture de cellules souches mésenchymateuses, selon la présente invention, augmente le nombre de cils primaires dans les cellules et allonge ceux-ci. La cellule souche mésenchymateuse ou le produit de culture de cellules souches mésenchymateuses, selon la présente invention, peut être utilisé(e) en tant que composition pharmaceutique pour prévenir ou traiter des maladies provoquées par une ciliopathie ou un dysfonctionnement ciliaire. La cellule souche mésenchymateuse ou le produit de culture de cellules souches mésenchymateuses, selon la présente invention, peut être utilisé(e) en tant que composition cosmétique. 본 발명은 중간엽 줄기세포 또는 중간엽 줄기세포의 배양물을 포함하는 섬모발생용 조성물을 제공한다. 본 발명에 따른 중간엽 줄기세포 또는 중간엽 줄기세포 배양물은 세포의 일차섬모의 수를 증가시킬 뿐 아니라, 길이를 신장시키는 효과가 있다. 본 발명에 따른 중간엽 줄기세포 또는 중간엽 줄기세포의 배양물은 섬모 형성 이상증 또는 섬모 손상으로 인한 질환의 예방 또는 치료용 약학적 조성물로 사용될 수 있다. 본 발명에 따른 중간엽 줄기세포 또는 중간엽 줄기세포의 배양물은 화장료 조성물로 사용될 수 있다.