BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

• Main Authors: PETTI, Antonio, SANTAGADA, Vincenzo, PERISSUTTI, Elisa, FRECENTESE, Francesco, FIORINO, Ferdinando, CIRINO, Giuseppe, MUSCARA', Marcelo, CALIENDO, Giuseppe, MAGLI, Elisa, ROVIEZZO, Fiorentina, SEVERINO, Beatrice
• Format: Patent
• Language: English; French
• Published: 30.09.2021
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; STEROIDS

The present invention relates to salts of budesonide 21-phosphate with β2 adrenergic agonists, preferably with formoterol, pharmaceutical compositions containing the same and the use thereof in the treatment of respiratory inflammatory pathologies, obstructive pathologies and allergen-induced airway dysfunctions. The invention further relates to the process for preparing said salts. La présente invention concerne des sels de budésonide 21-phosphate ayant des agonistes de β2 adrénergique, de préférence du formotérol, des compositions pharmaceutiques les contenant et leur utilisation dans le traitement de pathologies inflammatoires respiratoires, de pathologies obstructives et de dysfonctionnements des voies respiratoires induits par des allergènes. La présente invention concerne en outre un procédé de préparation desdits sels.