METHODS AND USE OF CHIMERIC PROTEINS

Provided are methods for using chimeric proteins to produce RNA modifications that can be detected by sequencing methods, including methods detecting relative translation rates of various mRNAs. Also provided herein are compositions comprising chimeric proteins, wherein the chimeric proteins compris...

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Bibliographic Details
Main Author YEO, Eugene
Format Patent
LanguageEnglish
French
Published 16.09.2021
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Summary:Provided are methods for using chimeric proteins to produce RNA modifications that can be detected by sequencing methods, including methods detecting relative translation rates of various mRNAs. Also provided herein are compositions comprising chimeric proteins, wherein the chimeric proteins comprise a RNA editing protein and a ribosomal protein. L'invention concerne des procédés d'utilisation de protéines chimériques pour produire des modifications d'ARN qui peuvent être détectées par des procédés de séquençage, y compris des procédés de détection de taux de traduction relatifs de divers ARNm. L'invention concerne également des compositions comprenant des protéines chimériques, les protéines chimériques comprenant une protéine d'édition d'ARN et une protéine ribosomale.
Bibliography:Application Number: WO2021US22150