IL-10 MUTEINS

The present disclosure relates to modified forms, or muteins, of IL-10, as well as variants thereof, which display improved features as compared to wild-type IL-10. The present invention further relates to the use of such modified forms, or muteins, of IL-10, as well as variants thereof in methods,...

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Bibliographic Details
Main Authors GORBY, Claire, GONZALEZ, Ignacio Moraga, MITRA, Suman
Format Patent
LanguageEnglish
French
Published 16.09.2021
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present disclosure relates to modified forms, or muteins, of IL-10, as well as variants thereof, which display improved features as compared to wild-type IL-10. The present invention further relates to the use of such modified forms, or muteins, of IL-10, as well as variants thereof in methods, including therapeutic methods. La présente divulgation concerne des formes modifiées, ou mutéines, d'IL-10, ainsi que des variants de celles-ci, qui présentent des caractéristiques améliorées par rapport à l'IL-10 de type sauvage. La présente invention concerne en outre l'utilisation de telles formes modifiées, ou mutéines, d'IL-10, ainsi que des variants de celles-ci, dans des méthodes, y compris des méthodes thérapeutiques.
Bibliography:Application Number: WO2021GB50592