METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS

The invention provides methods of making immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions generated by such methods. L'invention concerne des méthodes de production de cellules effectrices immunitaires (par exemple, des lymp...

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Main Authors GUIMARAES, Carla, KOSHY, Sandeep Tharian, BROGDON, Jennifer, JAYASHANKAR, Shyamali, STEIN, Andrew Marc, KODRASI, Olja, TREANOR, Louise, LIM, Hyungwook, PRATICO, Elizabeth Dorothy, PRICE, Andrew, YANG, Jennifer, GRANDA, Brian Walter, DRANOFF, Glenn, GREENE, Michael R, RAYO, Amy, ZHU, Xu, MILLER, Sandra, CEBE, Regis, HACK, Anniesha, ENGELS, Boris, SOHONI, Akash, BONDANZA, Attilio, BARDROFF, Michael
Format Patent
LanguageEnglish
French
Published 21.10.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention provides methods of making immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions generated by such methods. L'invention concerne des méthodes de production de cellules effectrices immunitaires (par exemple, des lymphocytes T, des cellules NK) qui expriment un récepteur antigénique chimérique (CAR), et des compositions générées au moyen desdites méthodes.
Bibliography:Application Number: WO2021US19889