COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS

Provided herein is a compound of formula (XXXII) or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer thereof or a physiologically functional derivative thereof, wherein R1, R2, R3, G, A, E, n, p, and q are defined herein. Also provided herein are compositions comprising a compound...

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Bibliographic Details
Main Authors WU, Xinyuan, TERKIELTAUB, Dov, SCHUTZ, Nili, CHENARD, Bertrand
Format Patent
LanguageEnglish
French
Published 05.08.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein is a compound of formula (XXXII) or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer thereof or a physiologically functional derivative thereof, wherein R1, R2, R3, G, A, E, n, p, and q are defined herein. Also provided herein are compositions comprising a compound of formula (XXXII), and methods of using a compound of formula (XXXII), e.g., in the treatment or prevention of skin disorders. L'invention concerne un composé de formule (XXXII) ou un sel, solvate, hydrate, stéréo-isomère pharmaceutiquement acceptables de celui-ci ou un dérivé physiologiquement fonctionnel de celui-ci, dans lequel R1, R2, R3, G, A, E, n, p, et q sont tels que définis dans la description. L'invention concerne également des compositions pharmaceutiques comprenant un composé de formule (I), et des procédés d'utilisation d'un composé de formule (XXXII), par exemple, dans le traitement ou la prévention de troubles cutanés.
Bibliography:Application Number: WO2021US15449