HEPATITIS A VIRUS PREPARATION METHOD AND HEPATITIS A VIRUS PREPARED ACCORDING TO METHOD

• Main Authors: LEE, Sujeen, CHO, Seo Young, KIM, Soo-young, LEE, Jung-eun, KIM, Hun, LEE, Kun Se
• Format: Patent
• Language: English; French; Korean
• Published: 24.06.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present invention relates to a hepatitis A virus production method and hepatitis A virus produced according to the method, and, more specifically, to: a hepatitis A virus production method and hepatitis A virus produced according to the method, the method comprising the step of infecting a host cell with a virus obtained by transforming a host cell with a vector comprising an expression cassette, which comprises a hepatitis A virus gene, for hepatitis A virus preparation, and subculturing same. La présente invention concerne un procédé de production de virus de l'hépatite A ainsi que le virus de l'hépatite A produit selon le procédé et, plus spécifiquement, un procédé de production du virus de l'hépatite A et le virus de l'hépatite A produit selon le procédé, Le procédé comprend l'étape consistant à infecter une cellule hôte avec un virus obtenu par transformation d'une cellule hôte avec un vecteur comprenant une cassette d'expression qui comprend un gène du virus de l'hépatite A, pour la préparation du virus de l'hépatite A, et la sous-culture de celui-ci. 본 발명은 A형 간염 바이러스의 생산방법 및 이 방법에 따라 생산된 A형 간염 바이러스에 관한 것으로, 보다 상세하게는 A형 간염 바이러스 유전자를 포함하는 A형 간염 바이러스 제조용 발현 카세트(Expression cassette)를 포함하는 벡터로 숙주세포를 형질전환하여 얻어진 바이러스를 숙주세포에 감염시켜 계대 배양하는 단계를 포함하는 A형 간염 바이러스 생산방법 및 이 방법에 따라 생산된 A형 간염 바이러스에 관한 것이다.