NOVEL INDAZOLE DERIVATIVE, AND USE THEREOF

The present invention relates to a novel indazole derivative, and a use thereof, wherein the indazole derivative has excellent TRIB2 or YAP inhibitory activity, and can be effectively used as a pharmaceutical composition for preventing or treating cancer, narcolepsy, and fasciitis. La présente inven...

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Bibliographic Details
Main Authors KIM, Pil Ho, KIM, Seong Hwan
Format Patent
LanguageEnglish
French
Korean
Published 24.06.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a novel indazole derivative, and a use thereof, wherein the indazole derivative has excellent TRIB2 or YAP inhibitory activity, and can be effectively used as a pharmaceutical composition for preventing or treating cancer, narcolepsy, and fasciitis. La présente invention concerne un nouveau dérivé d'indazole et son utilisation ; le dérivé d'indazole ayant une excellente activité inhibitrice de TRIB2 ou YAP, et pouvant être utilisé de manière efficace en tant que composition pharmaceutique pour la prévention ou le traitement du cancer, de la narcolepsie et de la fasciite. 본 발명은 신규한 인다졸 유도체 및 이의 용도에 관한 것으로, 상기 인다졸 유도체는 TRIB2 또는 YAP 저해 활성이 우수하여 암, 기면증 및 근막염 예방 또는 치료용 약학 조성물로 유용하게 사용가능하다.
Bibliography:Application Number: WO2020KR18477