MULTIDRUG EFFLUX PUMP VARIANT, POLYNUCLEOTIDE CODING VARIANT, MICROORGANISM COMPRISING VARIANT, AND METHOD FOR PRODUCING VIOLACEIN OR DEOXYVIOLACEIN USING SAME

• Main Authors: RYU, Gyu Ri, BAE, Hyun Ae, JEON, Ae Ji, JANG, Jae Woo
• Format: Patent
• Language: English; French; Korean
• Published: 24.06.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present invention relates to a multidrug efflux pump (mepA) variant, a polynucleotide that codes the variant, a microorganism comprising the variant, and a method for producing violacein or deoxyviolacein using same, the present invention being usefully applicable to the mass production of violacein or deoxyviolacein. La présente invention concerne une variante de pompe d'efflux multimédicament (mepA), un polynucléotide qui code pour la variante, un micro-organisme comprenant la variante et un procédé de production de violacéine ou de désoxyviolacéine les utilisant, la présente invention pouvant être appliquée de façon utile à la production en masse de violacéine ou de désoxyviolacéine. 다중약물 유출펌프(multidrug efflux pump, mepA) 변이체, 상기 변이체를 코딩하는 폴리뉴클레오티드, 상기 변이체를 포함하는 미생물, 및 이를 이용하여 비올라세인(violacein) 또는 디옥시비올라세인(deoxyviolacein)을 제조하는 방법에 관한 것으로, 비올라세인 또는 디옥시비올라세인의 대량 생산에 유용하게 사용될 수 있다.