1,2,4-OXADIAZOLE DERIVATIVES AS LIVER X RECEPTOR AGONISTS

Provided herein are compounds and pharmaceutical compositions useful for treating meibomian gland dysfunction (MGD), comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I) or a compound of Formula (I'), or pharmaceutical composition...

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Bibliographic Details
Main Authors LINKENS, Kathryn Taylor, SMITH, Jeffrey, SHAW, Duncan, FLYER, Alec Nathanson, HARDY, Declan, MA, Fupeng, BOSS, Kelly D, LOREN, Jon Christopher, FAN, Yi, MOLTENI, Valentina, SOLOVAY, Catherine Fooks, HUANG, Zhihong
Format Patent
LanguageEnglish
French
Published 03.06.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are compounds and pharmaceutical compositions useful for treating meibomian gland dysfunction (MGD), comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I) or a compound of Formula (I'), or pharmaceutical composition described herein. L'invention concerne des composés et des compositions pharmaceutiques utiles pour traiter un dysfonctionnement de la glande de Meibomius (MGD), comprenant l'administration à un sujet qui en a besoin d'une quantité thérapeutiquement efficace d'un composé de formule (I) ou d'un composé de formule (I'), ou de la composition pharmaceutique décrite ici.
Bibliography:Application Number: WO2020IB61053