PROSTAGLANDIN ANALOGS AND USES THEREOF

The present invention relates to a pharmaceutical composition for the prevention or treatment of a disease, disorder, or condition associated with Nurr1, including, as an active ingredient, a prostaglandin analog or a pharmaceutically acceptable salt thereof, wherein the compound has excellent effec...

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Main Authors RAJAN, Sreekanth, YOON, Ho Sup, YOON, Cheolhwan, KIM, Moonhwan, SEO, Jeongbeob, HAN, Cheolkyu, KANG, Hongjun, YOO, Jun Yeob
Format Patent
LanguageEnglish
French
Published 14.05.2021
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Abstract The present invention relates to a pharmaceutical composition for the prevention or treatment of a disease, disorder, or condition associated with Nurr1, including, as an active ingredient, a prostaglandin analog or a pharmaceutically acceptable salt thereof, wherein the compound has excellent effects in inducing Nurr1, and thus, can be useful as a pharmaceutical composition for the prevention or treatment of a disease, disorder, or condition associated with Nurr1, in particular, cancer, autoimmune disease such as rheumatoid arthiritis, schizophrenia, manic depression and neurodegenerative disease such as Alzheimers disease or Parkinson's disease. La présente invention concerne une composition pharmaceutique pour la prévention ou le traitement d'une maladie, trouble, ou un état associé à Nurr1, comprenant, en tant que principe actif, un analogue de prostaglandine ou un sel pharmaceutiquement acceptable de celui-ci, le composé ayant d'excellents effets dans l'induction de Nurr1, et peut ainsi être utile en tant que composition pharmaceutique pour la prévention ou le traitement d'une maladie, de troubles ou d'états associés à Nurr1, en particulier, le cancer, les maladies auto-immunes telles que la polyarthrite rhumatoïde, la schizophrénie, la dépression maniaque et les maladies neurodégénératives telles que la maladie d'Alzheimer ou la maladie de Parkinson.
AbstractList The present invention relates to a pharmaceutical composition for the prevention or treatment of a disease, disorder, or condition associated with Nurr1, including, as an active ingredient, a prostaglandin analog or a pharmaceutically acceptable salt thereof, wherein the compound has excellent effects in inducing Nurr1, and thus, can be useful as a pharmaceutical composition for the prevention or treatment of a disease, disorder, or condition associated with Nurr1, in particular, cancer, autoimmune disease such as rheumatoid arthiritis, schizophrenia, manic depression and neurodegenerative disease such as Alzheimers disease or Parkinson's disease. La présente invention concerne une composition pharmaceutique pour la prévention ou le traitement d'une maladie, trouble, ou un état associé à Nurr1, comprenant, en tant que principe actif, un analogue de prostaglandine ou un sel pharmaceutiquement acceptable de celui-ci, le composé ayant d'excellents effets dans l'induction de Nurr1, et peut ainsi être utile en tant que composition pharmaceutique pour la prévention ou le traitement d'une maladie, de troubles ou d'états associés à Nurr1, en particulier, le cancer, les maladies auto-immunes telles que la polyarthrite rhumatoïde, la schizophrénie, la dépression maniaque et les maladies neurodégénératives telles que la maladie d'Alzheimer ou la maladie de Parkinson.
Author RAJAN, Sreekanth
YOON, Ho Sup
YOO, Jun Yeob
KIM, Moonhwan
YOON, Cheolhwan
SEO, Jeongbeob
KANG, Hongjun
HAN, Cheolkyu
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– fullname: HAN, Cheolkyu
– fullname: KANG, Hongjun
– fullname: YOO, Jun Yeob
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DocumentTitleAlternate ANALOGUES DE LA PROSTAGLANDINE ET LEURS UTILISATIONS
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YOO, Ook Joon
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Snippet The present invention relates to a pharmaceutical composition for the prevention or treatment of a disease, disorder, or condition associated with Nurr1,...
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CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Title PROSTAGLANDIN ANALOGS AND USES THEREOF
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