ESCHERICHIA COLI COMPOSITIONS AND METHODS THEREOF

• Main Authors: ANDERSON, Annaliesa Sybil, KIM, Jin-Hwan, CHORRO, Laurent Oliver, MERCHANT, Nishith, STEAD, David Robert, LOMBERK, Scott Ellis, CHU, Ling, SINGH, Suddham, DONALD, Robert G.K, GRIFFOR, Matthew Curtis, KODALI, Srinivas, CHEN, Wei, PAN, Rosalind, GUAN, Zeqiang, LOTVIN, Jason Arnold, TAKANE, Karen Kiyoko, PRASAD, Avvari Krishna, RUPPEN, Mark Edward, GU, Jianxin, MORAN, Justin Keith
• Format: Patent
• Language: English; French
• Published: 06.05.2021
• Subjects: CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES

In one aspect, the invention relates to a polypeptide derived from E. coli and a fragment thereof, including compositions and methods thereof. Also disclosed herein are compositions that include a polypeptide derived from E. coli and a fragment thereof; and modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof. In a further aspect, disclosed herein are mammalian host cells that include sequence(s) encoding a polypeptide derived from E. coli or fragments thereof. Selon un aspect, l'invention concerne un polypeptide issu d'E. coli et un fragment de celui-ci, ainsi que des compositions et des procédés associés. L'invention concerne également des compositions qui comprennent un polypeptide issu d'E. coli et un fragment de celui-ci ; et des molécules de polysaccharide O modifiées issues de lipopolysaccharides d'E. coli et des conjugués de celles-ci. Selon un autre aspect, l'invention concerne des cellules hôtes de mammifère qui comprennent une ou des séquences codant pour un polypeptide issu d'E. coli ou des fragments de celles-ci.