PEPTIDE FOR REDUCING HAIR LOSS AND PROMOTING HAIR GROWTH, AND COSMETIC COMPOSITION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

• Main Authors: KIM, Heungjae, PARK, Keedon, SHIN, Kayoung, CHUNG, Hwa-Jee
• Format: Patent
• Language: English; French; Korean
• Published: 10.06.2021
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

The present invention relates to a peptide for reducing hair loss or promoting hair growth, and a cosmetic composition and a pharmaceutical composition comprising same, and specifically, a cosmetic composition, and a pharmaceutical composition for treatment may be provided, which are capable of reducing hair loss and promoting hair growth by activating a Wnt/β-catenin signaling pathway, and at the same time, promoting the activity of the collagenase MMP-2 and ALP proteins and growth hormones needed for hair growth. La présente invention concerne un peptide pour réduire la perte des cheveux ou favoriser la pousse des cheveux, et une composition cosmétique et une composition pharmaceutique le comprenant, et plus précisément, une composition cosmétique et une composition pharmaceutique destinées au traitement peuvent être fournies, qui sont capables de réduire la perte des cheveux et de favoriser la pousse des cheveux par activation d'une voie de signalisation Wnt/β-caténine, et en même temps, de favoriser l'activité des protéines de collagénase MMP-2 et ALP et des hormones de croissance nécessaires à la pousse des cheveux. 본 발명은 탈모 완화 또는 모발 성장을 촉진하는 펩타이드, 이를 포함하는 화장료 조성물 및 약학적 조성물에 관한 것으로, 구체적으로는 Wnt/β-카테닌 신호전달 경로를 활성화하고, 동시에 모발 성장에 필요한 성장 호르몬들과 콜라게나아제 MMP-2 및 ALP 단백질 활성을 촉진하여, 탈모를 완화하고 모발 성장을 촉진할 수 있는 화장료 조성물 및 치료용 약학적 조성물을 제공할 수 있다.