COMPOUNDS FOR IMMUNOMODULATION

The invention relates to compounds based on a recombinant form of the CCP6 region of C4BP and an oligomerization domain for use in the prevention and/or treatment of immunological diseases. Moreover, the invention relates to methods for obtaining tolerogenic dendritic cells and tolerogenic macrophag...

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Bibliographic Details
Main Authors SERRANO SANTACRUZ, Inmaculada, ARAN PERRAMON, Josep M, LUQUE GÓMEZ, Ana
Format Patent
LanguageEnglish
French
Published 22.04.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to compounds based on a recombinant form of the CCP6 region of C4BP and an oligomerization domain for use in the prevention and/or treatment of immunological diseases. Moreover, the invention relates to methods for obtaining tolerogenic dendritic cells and tolerogenic macrophages using the compounds of the invention and to the cells obtained by these methods and their therapeutic uses. L'invention concerne des composés basés sur une forme recombinante de la région CCP6 de C4BP et un domaine d'oligomérisation destiné à être utilisé dans la prévention et/ou le traitement de maladies immunologiques. De plus, l'invention concerne des procédés pour obtenir des cellules dendritiques tolérogènes et des macrophages tolérogènes à l'aide des composés de l'invention et les cellules obtenues selon ces procédés et leurs utilisations thérapeutiques.
Bibliography:Application Number: WO2020EP79374