PREPARATION OF PYRAZOLO[3,4-B]PYRIDINES AS ANTIMALARIALS

The present invention relates to pyrazolo[3,4-b]pyridine compounds. The present invention further relates to methods for inhibiting Plasmodium comprising contacting Plasmodium with pyrazolo[3,4-b]pyridine compounds described herein. Also described herein are methods of treating malaria comprising ad...

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Bibliographic Details
Main Authors GUY, Rodney Kiplin, EAGON, Scott Charles, HAMMILL, Jared T
Format Patent
LanguageEnglish
French
Published 08.04.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to pyrazolo[3,4-b]pyridine compounds. The present invention further relates to methods for inhibiting Plasmodium comprising contacting Plasmodium with pyrazolo[3,4-b]pyridine compounds described herein. Also described herein are methods of treating malaria comprising administering pyrazolo[3,4-b]pyridine compounds to a subject in need thereof. La présente invention concerne des composés de pyrazolo [3,4-b] pyridine. La présente invention concerne en outre des méthodes d'inhibition de plasmodium consistant à mettre le plasmodium en contact avec des composés de pyrazolo [3,4-b] pyridine de la présente invention. L'invention concerne également des méthodes de traitement du paludisme consistant à administrer des composés de pyrazolo [3,4-b] pyridine à un patient qui en a besoin.
Bibliography:Application Number: WO2020US54315