CR2 BINDING PROTEINS AND THEIR USE IN MEDICAL THERAPY

The present invention provides CR2 binding proteins which bind to human CR2, pharmaceutical compositions comprising said CR2 binding proteins and their use in the treatment or prevention of autoimmune and/or inflammatory conditions, infectious diseases and malignancies associated with the Epstein-Ba...

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Main Authors ELLSON, Christian, HOOK, Laura J, LEKOVA, Eleanora, KITCHEN, Semra, DOS SANTOS CRUZ DE MANTOS, Gabriela, MADURA, Emilie, BAILEY, James Matthew, BURDEN, Michael Neil, ZHANG, Jian, NISTALA, Kiran, BOUMA, Gerben, DIMECH, Caroline J, DIXON, David
Format Patent
LanguageEnglish
French
Published 04.03.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides CR2 binding proteins which bind to human CR2, pharmaceutical compositions comprising said CR2 binding proteins and their use in the treatment or prevention of autoimmune and/or inflammatory conditions, infectious diseases and malignancies associated with the Epstein-Barr virus (EBV); and their use as vaccine adjuvants/antigen carriers. La présente invention concerne des protéines de liaison CR2 qui se lient au CR2 humain, des compositions pharmaceutiques comprenant lesdites protéines de liaison CR2 et leur utilisation dans le traitement ou la prévention de maladies auto-immunes et/ou inflammatoires, de maladies infectieuses et de malignités associées au virus d'Epstein-Barr (EBV); et leur utilisation en tant qu'adjuvants de vaccins/porteurs d'antigènes.
Bibliography:Application Number: WO2020EP74049