METHOD FOR PRODUCING SMALL INTESTINAL EPITHELIUM-LIKE CELLS

• Main Authors: NEGORO, Ryosuke, MIZUGUCHI, Hiroyuki, TOSAKA, Yasuhiro, TAKAYAMA, Kazuo, NAGATA, Ryousuke, HATSUYAMA, Asako, ENOKI, Tatsuji
• Format: Patent
• Language: English; French; Japanese
• Published: 30.12.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

According to the present invention, a method for producing small intestinal epithelium-like cells is provided, which comprises the steps of: (i) culturing small intestinal epithelium progenitor cells in a culture medium containing active vitamin D; and (ii) acquiring small intestinal epithelium-like cells. La présente invention concerne un procédé de production de petites cellules du type épithélium intestinal, comprenant les étapes suivantes: (i) la culture de petites cellules progénitrices d'épithélium intestinal dans un milieu de culture contenant de la vitamine D active ; et (ii) l'acquisition de petites cellules du type épithélium intestinal. 本発明によれば、以下の工程を含む小腸上皮様細胞の製造方法； （ｉ）小腸上皮前駆細胞を、活性型ビタミンＤを含む培地で培養する工程；及び （ｉｉ）小腸上皮様細胞を取得する工程 が提供される。