NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF

Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a bind...

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Bibliographic Details
Main Authors CHU, David Sai-Ho, ARIAS, Joel Daniel, BURKE, Rob, DOPPALAPUDI, Venkata Ramana, COCHRAN, Michael Caramian
Format Patent
LanguageEnglish
French
Published 10.12.2020
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
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Summary:Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer. L'invention concerne des compositions et des formulations pharmaceutiques qui comprennent un fragment de liaison conjugué à une molécule d'acide polynucléique et un polymère. L'invention concerne également des méthodes pour traiter un cancer qui font intervenir une composition ou une formulation pharmaceutique comprenant un fragment de liaison conjugué à une molécule d'acide polynucléique et un polymère.
Bibliography:Application Number: WO2020US36369