PROCESS FOR PREPARING 1-DEOXY-1-METHYLAMINO-D-GLUCITOL 2-(3,5-DICHLOROPHENYL)-6-BENZOXAZOLECARBOXYLATE
The present invention relates to an improved process for the preparation of 1-deoxy-1-methylamino-D- glucitol 2-(3,5-dichlorophenyl)-6-benzoxazolecarboxylate, also known as tafamidis meglumine. The process of the present invention is particularly suitable for industrial scale manufacture of tafamidi...
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Main Authors | , |
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Format | Patent |
Language | English French |
Published |
15.10.2020
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to an improved process for the preparation of 1-deoxy-1-methylamino-D- glucitol 2-(3,5-dichlorophenyl)-6-benzoxazolecarboxylate, also known as tafamidis meglumine. The process of the present invention is particularly suitable for industrial scale manufacture of tafamidis meglumine with excellent purity and high yields.
La présente invention concerne un procédé amélioré pour la préparation de 1-désoxy-1-méthylamino-D-glucitol 2- (3,5-dichlorophényl)-6-benzoxazolecarboxylate, également connu sous le nom de méglumine. Le procédé de la présente invention est particulièrement approprié pour la fabrication à l'échelle industrielle de tafamidis méglumine avec une pureté excellente et des rendements élevés. |
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Bibliography: | Application Number: WO2020EP57683 |