COLLAGENASE FORMULATIONS AND METHODS OF PRODUCING THE SAME

Disclosed herein are improved collagenase-containing formulations and methods of preparing the same. The collagenase-containing formulations comprise a collagenase, about 30 mM to about 240 mM of a disaccharide, about 50 mM to about 800 mM of mannitol, and about 6 mM to about 10 mM of a Tris-HCl. Ly...

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Bibliographic Details
Main Author SUKURU, Karunakar
Format Patent
LanguageEnglish
French
Published 09.07.2020
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Summary:Disclosed herein are improved collagenase-containing formulations and methods of preparing the same. The collagenase-containing formulations comprise a collagenase, about 30 mM to about 240 mM of a disaccharide, about 50 mM to about 800 mM of mannitol, and about 6 mM to about 10 mM of a Tris-HCl. Lyophilized and reconstituted formulations are also provided. La présente invention concerne des formulations contenant une collagénase et leurs procédés de préparation. Les formulations contenant une collagénase comprennent une collagénase, d'environ 30 mM à environ 240 mM d'un disaccharide, d'environ 50 mM à environ 800 mM de mannitol et d'environ 6 mM à environ 10 mM d'un Tris-HCl. L'invention concerne également des formulations lyophilisées et reconstituées.
Bibliography:Application Number: WO2020US12202