SUBSTITUTED 3-((3-AMINOPHENYL)AMINO)PIPERIDINE-2,6-DIONE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

Provided herein are piperidine dione compounds having the following structure (I) wherein RN, R1, R2, R3, R4, L,V, m, and n are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease....

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Main Authors PAPA, Patrick, KERCHER, Timothy, NAGY, Mark, SU, Shuichan, BAHMANYAR, Sogoie, NARLA, Rama, WHITEFIELD, Brandon, AMMIRANTE, Massimo, HANSEN, Joshua, HORN, Evan, CORREA, Matthew, NORRIS, Stephen, NAYAK, Surendra, MAYNE, Christopher, SAPIENZA, John, GRANT, Virginia, PLANTEVIN-KRENITSKY, Veronique
Format Patent
LanguageEnglish
French
Published 25.06.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Provided herein are piperidine dione compounds having the following structure (I) wherein RN, R1, R2, R3, R4, L,V, m, and n are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease. L'invention concerne des composés de pipéridine dione ayant la structure suivante (I) dans laquelle RN, R1, R2, R3, R4, L, V, m, et n sont tels que définis dans la description, des compositions comprenant une quantité efficace d'un composé de pipéridine dione, et des procédés de traitement ou de prévention d'une maladie médiée par un récepteur d'androgène.
Bibliography:Application Number: WO2019US67088