PROCESS FOR THE PREPARATION OF SARTANS OR SALTS THEREOF

Aspects of the present application relate to process for the preparation of Sartan or salt thereof containing less than 0.05 ppm of N-nitrosoalkylamine impurities. Process of present application is useful to obtain Sartan or salt thereof selected from Valsartan, Candesartan cilexetil, Losartan potas...

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Main Authors P, Srinivasa Rao, B, Laxmi, D, Kasi Reddy, ADLA, Vijaya Kumar, KODIGANTI, Venkatesh, CHETLUR, Kiran kumar, KARRI, Vijaya Kumar, BANDREDDI, Veeranjaneyulu, BANDICHHOR, Rakeshwar, BUDHDEV, Rajeev Rehani, FENIL, Soni
Format Patent
LanguageEnglish
French
Published 25.06.2020
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Summary:Aspects of the present application relate to process for the preparation of Sartan or salt thereof containing less than 0.05 ppm of N-nitrosoalkylamine impurities. Process of present application is useful to obtain Sartan or salt thereof selected from Valsartan, Candesartan cilexetil, Losartan potassium and Irbesartan, containing less than 0.05 ppm of N-nitrosoalkylamine impurities. Des aspects de la présente invention concernent un procédé pour la préparation de sartan ou d'un sel de celui-ci contenant moins de 0,05 ppm d'impuretés de N-nitrosoalkylamine. Le procédé de la présente invention est utile pour obtenir un sartan ou un sel de celui-ci choisi parmi le valsartan, le candésartan cilexetil, le losartan potassique et l'irbésartan, contenant moins de 0,05 ppm d'impuretés de N-nitrosoalkylamine.
Bibliography:Application Number: WO2019IB51401