PROCESS FOR THE PREPARATION OF A CYCLIC DINUCLEOTIDE

The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist of the following formula (I), involving the use of compounds A and B. L'invention concerne d'une manière générale des procédés améliorés de préparation d...

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Main Authors TREITLER, Daniel S, SEZEN EDMONDS, Melda, PURDUM, Geoffrey Eugene, YU, Miao, SCHMIDT, Michael Anthony, FREITAG, Adam Joseph, ROGERS, Amanda J, HANG, Chao, ZHENG, Bin, YUAN, Changxia, COHEN, Benjamin M, GUO, Siwei, ZHU, Jason J
Format Patent
LanguageEnglish
French
Published 11.06.2020
Subjects
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Summary:The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist of the following formula (I), involving the use of compounds A and B. L'invention concerne d'une manière générale des procédés améliorés de préparation d'un dinucléotide cyclique qui est utile en tant qu'agoniste de STING de formule suivante (I) : (I) impliquant l'utilisation des composés A et B : Composé A, Composé B.
Bibliography:Application Number: WO2019US64137